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Adenosine is an endogenous nucleoside
2024-11-27
Adenosine is an endogenous nucleoside that plays pivotal roles in different physiological and pathophysiological processes by triggering specific cell-surface receptors both in the 3X FLAG mg and in the periphery. The adenosine receptors (ARs) are four different subtypes of G protein-coupled recept
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All scientific data over the years
2024-11-27
All scientific data over the years points that 5α-reductase inhibitors undoubtedly are an effective treatment for BPH and associated LUTS, having a favorable risk-benefit profile. In contrast, although some studies indicated positive results, there is still no consensus about their use in BPH or PC
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Several genes related to metabolism post transcriptional
2024-11-27
Several genes related to metabolism, post-transcriptional regulation, chromatin structure, and signaling pathways are required for the sexual development and virulence of G. zeae (Baldwin et al., 2010, Bluhm et al., 2007, Ding et al., 2009, Han et al., 2007, Hou et al., 2002, Jenczmionka et al., 200
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Suspecting that ACL might regulate the
2024-11-27
Suspecting that ACL might regulate the expression or activity of myogenic transcription factors, Das knocked down MyoD and found that such intervention abolished the effect of ACL on fast MyHC expression and that, conversely, MyoD overexpression partially rescued reduced fast MyHC expression caused
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adrenergic receptors There are however concerns of potential
2024-11-27
There are however, concerns of potential side-effects that should also be taken into account. Even though some studies pointed towards a potentially greater radiosensitising effect in p53-deficient tumours, ATM inhibition radiosensitises adrenergic receptors in general, which raises the concern of
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Introduction Apoptosis signal regulating kinase ASK a family
2024-11-27
Introduction Apoptosis signal-regulating kinase 1 (ASK1), a family member of the mitogen-activated protein (MAP) kinase kinase kinase (MAP3K) family, selectively activates the JNK and p38 MAP kinase pathways in response to various types of stresses, including oxidative stress, and subsequently indu
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The mechanism governing how mechanotransduction
2024-11-27
The mechanism governing how mechanotransduction signals regulate a number of genes involved in cartilage hemostasis remains unclarified. Mitogen-activated protein kinase (MAPK) pathways are activated by static and dynamic compression of cartilage (31 32). c-Fos/AP-1 is downstream of the MAPK pathway
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Previously we have detected the
2024-11-27
Previously, we have detected the expression of APJ receptor on stomach projecting Prostaglandin E2 in DMV, in addition, icv administration of apelin-13 induced a remarkable c-Fos activation in those cells which were previously marked by a retrograde neuronal tracer fast blue (Birsen et al., 2016). M
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Dopaminergic neurons are vulnerable to oxidative products
2024-11-27
Dopaminergic neurons are vulnerable to oxidative products and inflammatory responses; these processes may play important roles in the etiology of PD. Because glial Tobramycin synthesis are the main generators of inflammatory responses in the CNS, the possibility that PD results from glial cell dysfu
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br Results br Discussion Control of
2024-11-27
Results Discussion Control of chronic inflammation is important in several inflammatory conditions like asthma, rheumatoid arthritis and fibrosis in lung diseases. The regulatory pathways that control chronic inflammation are complex and multi-factorial. Over expression of inflammatory mediato
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br Introduction Natural antioxidants in vegetables
2024-11-27
Introduction Natural antioxidants, in vegetables, have gained the attention of both researchers and consumers. Vegetable amaranth (Amaranthus tricolor) is a good source of minerals, vitamins, phenolics, and carotenoids; it also contains betalains, a nitrogen containing group of natural pigments,
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Although the gene that encodes
2024-11-27
Although the gene that encodes DHFR has been strongly conserved during evolution, subtle differences in the active sites of bacterial, human and parasite Fenoprofen Calcium have been exploited to develop DHFR inhibitors specific to particular pathogens 1, 3. For example, pyrimethamine and cycloguan
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Nifedipine receptor Current treatment options for corneal ne
2024-11-27
Current treatment options for corneal neovascularization include topical application of steroids220, 25, 35, 43 or surgical interventions: laser ablation,14, 203, 234, 48 photodynamic therapy (PDT),4, 93 and fine-needle diathermy.221, 238, 240, 261 Targeting proangiogenic molecules with topical or s
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Although our sample size is
2024-11-27
Although our sample size is not enough to conclude that there is no great genetic variation of the AR gene in most New World monkeys, it would be reasonable to state that the microsatellite region in the exon 1 of the androgen receptor gene of New World monkeys (platyrrhine) is relatively shorter th
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br Materials and Methods br Results In
2024-11-26
Materials and Methods Results In the Base Analysis (53% of patients having access to the ALK test in both Current and Alternative Scenarios), a total of 16,583 patients were tested of whom 1,252 were assumed to be ALK-positive. A more extensive use of Ventana in the Alternative Scenario determ
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